|
| |
|
click here to go to "Maggi's
background"
|
 |
About Paul |
Paul
writes: I was born
in 1950 and raised on Ballylough
Farm, in Jerrettspass, near Newry, Co Down, Northern Ireland, where my
family have farmed for several generations.
My academic career went like this: BSc
(Hons.) Biochemistry (1969-1973). Queens University, Belfast. |
|
MSc
in Immunology (1974-1976). Dept. of Applied Biology, Brunel University
(while working at the National Institute for Medical Research, Mill Hill,
London).
PhD
in Immunology (1976-1980). Department of Anatomy, University of
Newcastle-upon-Tyne.
|
The
rest of my career went like this as in my following CV:
Research
posts Non-academic work
Teaching Experience
[ PAUL'S SCIENTIFIC PUBLICATIONS ] [ Paul's PhD thesis in Immunology ]

Research
Posts held
 |
Research
Officer. Division of Immunology,
The National Institute for Medical Research, London. October
1973-September 1976. (My MSc at Brunel University was undertaken while I
was working at the National Institute). |
Here I worked on mechanism of
induction of tolerance to artificial antigens in B-lymphocytes, both in
vivo and in vitro. Part of
this work formed the basis of my MSc research project (see publications 1
& 2 below). I left this
post to take up a place at the University of Newcastle upon Tyne as a PhD
student. Following
the award of my PhD, I became:
 |
Postdoctoral Fellow in Immunology.
Department of Pathology, McMaster University Medical Centre, Hamilton,
Ontario, Canada from August 1980 - August 1983. |
In
this job I worked on the modulation of the immune response to synthetic
antigens by the parasitic nematode, Nippostrongylus
brasiliensis with particular attention to the effects on different
antibody classes, functional assays of the effects of cimetidine in
parasitic infection and the role of anti - idiotypic antibodies in
parasite - induced immunosuppression.
I
also carried out work on the effect of organochlorine contamination on
humoral immune responses of rainbow trout and Canadian salmon. On
returning to the UK in 1983 I took the post of :
 |
Senior Scientific
Officer. Department of Clinical Immunology, Addenbrooke’s Hospital,
Cambridge. |
This
involved investigating modulation of the antibody response to tetanus
toxoid and pneumovax vaccines in humans with deficient immune systems for
a variety of reasons. These included work with heart and heart/lung
transplant recipients who were receiving the anti-rejection drug
cyclosporin A, congenitally immunodeficient patients and a congenitally
asplenic woman. I also had responsibility for investigating cases of
selective antibody deficiency within the Cambridge Health Authority area.
My
most recent work in medical research has been in:
 |
The School of Respiratory
Medicine at Nottingham University on an Ethiopia-based project exploring
the possible role played by parasites in the development of asthma. |
 |
Before that, as
Postdoctoral Research
Assistant. Department of Life Sciences, University of Nottingham, (Nottingham.
April 1996 – end of 1997), I was
employed on a project, funded by the European Community and being carried
out jointly with groups in Brazil and France, studying the immune
responses of Brazilian children to gut parasitic nematodes, particularly
with respect to correlation of their immune responses with rates of
re-infection after chemotherapy and the effects of multiple infections on
immunity. |
My work has involved ELISA assays of IgE and IgG4 antibodies to Ascaris
lumbricoides, Trichuris trichiura and hookworms. Further work which
could be done, if funding becomes available, would be to measure
antibodies of other isotypes, correlate antibody and parasitological data
with measurements of cytokine levels and identify major antigens involved
in responses by Western blotting.
 |
Since
the end of this project I have done teaching and research in Nottingham
University School of Biology on an free-lance basis; most recently
working on a project to study the effect of concomitant Plasmodium
chabaudi infection on the immune response of
mice to Ascaris suum. |
My
non-academic work:
In
1989, I decided to take a break from my career and I moved to Nottingham when my partner,
Maggi (now my wife) became severely disabled
and I virtually became her full-time carer. At that point my concern about
her health left me unable to concentrate on academic pursuits. In the
intervening years, I have had various part-time and temporary jobs (work
in organic farming and running a wholefood shop) and also training in
disability awareness, something which is obviously of great personal
interest to me.
I
have been a member of the British Society for Immunology since 1975 (with
a few years break during the time when I was not working in research) and
of the British Society for Parasitology since March 1997.
In addition to nutritional information an
supply of nutritional supplements, I'm presently also running "The Helping
Hand" which provides assistance and advice, and finds accessible
accomodation for disabled people holidaying in South Tenerife.
TEACHING
EXPERIENCE
During
the course of my postdoctoral work in Canada, I participated in teaching a
course in advanced immunology to graduate students. I have also recently
supervised an MSc student and taught a course of immunology lectures and
practicals for first year students at Nottingham University in 1997 &
1999.
Return to top
Return to: Collective Ability Home Page

|
|
Maggi's Background
& CV |
Marguerite is English. She was born in Chelmsford,
in July 1948. Her first two years were lived in a cottage on a farm in
Bowers Gifford in rural Essex where her East End London-born mother learnt
- slowly and painfully - the art of drawing water from a well and how to
push a pram over dirt paths whilst wearing Wellington boots. |
|
That stage in her life came to an end in
June 1950 when she caught Polio and spent 15 months in hospital. The bout
of polio was severe and left her paralysed from the neck down. Her immune
system finally managed to defeat the polio virus before her lungs gave out
(she was too small for an iron lung and her father was told to expect her
death.)
A year's intensive boot-camp like
physiotherapy got her sitting up unaided and then standing and walking
(and falling over) with two elbow crutches and two full leg braces. In the
meantime, her parents had moved to one of post-war Britain's first Council
Estates, and when Maggi was discharged it was to a strange house peopled
by strangers who (to their distress) she called "Lady" and
"Man". It wasn't surprising that she her parents were unknown to
her - she had seen them for about an hour a week between the ages of
23months and 3½ years.
Time passed. School and hospital
alternated rhythmically until her mid-teens. Her education was put on hold
until after she reached her 16th birthday and left the profoundly limiting
environment of a special school for "delicate" children. (An
early tentative diagnosis of brain injury had been clung to by the school
authorities and she was placed with what we now no doubt call
"educationally challenged" children...)
However, intensive courses at Queen
Elizabeth Training College and Thurrock Technical College - in such
unlikely subjects as book-keeping, British Constitution, Russian and
typing - led to Essex and then Nottingham University and a BA(Hons) in Politics
and an MA in Social Work.
By her early 20s she had largely put
"disability" behind her, having only a leg brace, a cane and
yearly bronchitis to remind her of her run-in with polio.

Return to top
of page
At Essex University she was part of the
egalitarian group of students and staff who formed the first ever "Niteline"
telephone counselling and support service. (Although they, with due regard
to orthography, spelt it "Nightline") Arranging for training
from the Samaritans and undergoing the training herself was part of her
involvement in setting up the project, and so Social Work and social work
management seemed and obvious choice of profession.
After working as a
social work assistant in south London, she moved to Nottingham University
for her MA and professional social work qualification. After qualification
in 1975, she worked with Nottinghamshire Social Services and then with a
national Charity then known as "The Spastics Society" and now
renamed "Scope". Management training with the Open University
followed and she joined the management team.
By the mid-eighties, management wasn't
enough, so Maggi started her own counselling and personal skills training
and education practice ("People Skills", offering courses such
as time and stress management and anti-discriminatory practice as well)
and also began training in psychotherapy to develop the skills she
offered.

First
person now: "Polio was still lingering,
though, and, like
a time bomb, it exploded in 1990, shattering both my career and my career
plans - and a good deal of my social life. (I've written a bit about this
in Social Worker's Tale) However, not everything in the '90s was bad - in
the midst of all the returning ill-health and my disbelief at my new
oh-so-circumscribed lifestyle - I met, lived with, and then married, Paul.
 |
As well as a having a deep scientific
knowledge base, Paul was sympathetic towards "complementary health
care", and explored what was known about what was happening to me -
and what we could do practically, not to fight it but to ameliorate it. |
 |
I
gradually regained vigor and health and learn to live a more relaxed and
gentle lifestyle, living within my bodily means, rather than pounding my
body into submission. Gradually, we realised that together we formed an
"ability collective", as both our intellectual skills and our
personalities dovetailed." |
|
Telling people how my increase in health
had come about was natural (particularly other "old polios", but
the lessons learnt and the knowledge gained crosses an extremely wide
range of people, we've discovered, with younger non-disabled people
putting a high value on preventative, protective health and well-being
measures) and the "ability collective" became formally
constituted as "Collective Ability".
And, having taught myself to design websites, what could be more natural
than to build this website with Paul?
Return to top of "Maggi's background"
Return to top
of page
[ Home ] [ Science ] [ Maggi's Story ] [ Contact Us ] [ About Us ]
|

|
This website was designed by
www.kiss-simplewebsolutions.co.uk
|